REVIEW ARTICLE: REPUBLICATION |
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Year : 2017 | Volume
: 3
| Issue : 3 | Page : 72-76 |
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Polycystic kidney disease
Stanislaw P Stawicki1, Gary Lombardo2
1 OPUS 12 Foundation, Bethlehem Chapter, PA, USA 2 OPUS 12 Foundation, Bethlehem Chapter; Department of Surgery, Division of Traumatology and Surgical Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Correspondence Address:
Stanislaw P Stawicki Department of Research and Innovation, St. Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA 18015 USA
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/IJAM.IJAM_86_16
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Key points: (a) Polycystic kidney disease (PKD) is one of the most common genetic disorders; (b) There are two main types of PKD– autosomal dominant (most common) and autosomal recessive; (c) Diagnosis of PKD relies on a combination of clinical history, family history, imaging studies (computed tomography, ultrasound) and clinical findings (hematuria, hypertension, proteinuria); (d) Extrarenal manifestations of PKD include hepatic cysts, pancreatic and intestinal cysts, colonic diverticula, inguinal and abdominal wall hernias, valvular heart disorders, and cerebral aneurysms; (e) Treatment is centered on ameliorating symptoms and providing supportive care– therapy consists of adequate analgesia for pain symptoms, antibiotics for urinary tract infections, antihypertensive medications, renal supportive therapy; (f) Surgical indications include surgical decompression of large cysts and renal transplantation for end-stage renal failure.
The following core competencies are addressed in this article: Medical knowledge and patient care.
Republished with permission from: Stawicki SP, Lombardo G. Polycystic kidney disease. OPUS 12 Scientist 2008;2(1):17-20.
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